With the development of lnternet,e-Business has gradually become a new model for business activity,however,the security of e-Business is a major bottleneck restricting the development of e-Business.Network with virtual private network(VPN) can reduce network costs and communication costs,increase flexibility and provide safe and smooth network for the corporations that do e-Business across regions.This article introduces the definition and the technological core of VPN,and researches and analyzes the VPN application in e-commerce.