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本文报道美国纽约-癌症中心(1975年1月～1980年12月)治疗231例经活检证实的胰腺外分泌腺癌的回顾性研究,并对各种治疗方法进行比较。其中3例因非经腹部手术治疗,故其后未统计在内。经腹部手术治疗的228例中,女93例,男135例,年龄分布为27～85岁,平均60岁。随访时间平均为5个月。手术切除率为16.9%。39例施行胰腺切除,平均存活率为18个月,手术后30天内死亡率为18%,住院死亡率为23%。其中19例施行常规外科切除,平均存活17个月,术后30天内及住院死亡率均为16%,出院后的16例中5例(31%)存活2年,最长的1例存活4.5年,而未切除组132例中4例(3%)存活2年。33例施行~(125)碘植入,仅有1例形成瘘管;平均存活期为8个月,30天内死亡率0%,住院死亡率3%,最长者已存活33个月。76例
This article reports a retrospective study of 231 biopsy-proven pancreatic exocrine adenocarcinomas from the New York-Cancer Center in the United States (January 1975-December 1980) and compares the various treatments. Three of these cases were not treated after abdominal surgery. Of the 228 cases treated by abdominal surgery, 93 were females and 135 males. The age distribution ranged from 27 to 85 years, with an average age of 60 years. The average follow-up time was 5 months. The surgical resection rate was 16.9%. In 39 patients who underwent pancreatic resection, the average survival rate was 18 months. Mortality was 18% within 30 days after surgery and hospitalization mortality was 23%. Of the 19 patients who underwent routine surgical resection, the average survival was 17 months, and the mortality rate was 16% within 30 days after surgery. In the 16 cases after discharge, 5 (31%) survived for 2 years, and the longest 1 survived 4.5%. In the year, 4 (3%) of the 132 patients in the unexcised group survived for 2 years. Thirty-three patients (125) implanted iodine and only one fistula formed; the average survival time was 8 months, the mortality rate was 0% within 30 days, the in-hospital mortality rate was 3%, and the longest survival rate was 33 months. 76 cases