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目的:探讨双氯芬酸钠利多卡因联合消旋山莨菪碱治疗肾绞痛的临床疗效和不良反应。方法:回顾性分析2010年10月至2012年6月我科收治的肾绞痛298例患者的临床资料,肾绞痛均为临床诊断病例,均应用双氯芬酸钠利多卡因2 ml肌注联合消旋山莨菪碱10 mg静脉滴注,用药45 min后进行疗效和副作用的判断。结果:本组298例肾绞痛患者中,显效201例(67.45%),有效92例(30.87%),总有效率98.32%,无效5例(1.68%);未见明显副作用。结论:双氯芬酸钠利多卡因联合消旋山莨菪碱治疗肾绞痛疗效显著,且无明显副作用,值得临床进一步推广应用。
Objective: To investigate the clinical efficacy and adverse reactions of diclofenac sodium and lidocaine combined with racemic anisodamine in the treatment of renal colic. Methods: The clinical data of 298 patients with renal colic who were admitted to our department from October 2010 to June 2012 were retrospectively analyzed. Renal colic were all clinically diagnosed. All the patients were given diclofenac sodium and lidocaine 2 ml intramuscularly Anisodamine 10 mg intravenous infusion, 45 min after treatment to determine the efficacy and side effects. Results: Of the 298 patients with renal colic, 201 cases (67.45%) were effective, 92 cases (30.87%) effective, 98.32% effective and 5 cases (1.68%) ineffective. No obvious side effects were observed. CONCLUSION: Diclofenac sodium and lidocaine combined with racimustine are effective in treatment of renal colic with no obvious side effects, which is worth further clinical application.