【摘 要】
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Background The aim of this study was to compare nasogastric (NG) feeding with nasojejunal (NJ) feeding when treating pediatric patients with acute pancreatitis (AP).Methods We performed a single-center,prospective,randomized,active-controlled trial involv
【机 构】
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Department of Gastroenterology,The Children’s Hospital,Zhejiang University School of Medicine,Hangzh
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Background The aim of this study was to compare nasogastric (NG) feeding with nasojejunal (NJ) feeding when treating pediatric patients with acute pancreatitis (AP).Methods We performed a single-center,prospective,randomized,active-controlled trial involving 77 pediatric patients with AP from April 2014 to December 2017.The patients were randomized into two groups:the NG tube feeding group (34 patients) and the NJ tube feeding group (33 patients).The primary outcome measures included the enteral nutrition intoler-ance,the length of tube feeding time,the recurrent pain of pancreatitis and complications.Results A total of 62 patients with AP (31 patients for each group) came into the final analysis.No differences were found in baseline characteristics,pediatric AP score and computed tomography severity score between the two groups.Three (9.7%)patients in the NG group and one (3.2%) patient in the NJ group developed intolerance (relative risk =3.00,95% confidence interval 0.33-27.29,P =0.612).The tube feeding time and length of hospital stay of the NG group were significantly shorter than those of the NJ group (P =0.016 and 0.027,respectively).No patient died in the trial.No significant differences were found in recurrent pain,complications,nutrition delivery efficacy,and side effects between the two groups.Conclusions NG tube feeding appears to be effective and safe for acute pediatric pancreatitis compared with NJ tube feeding.In addition,high qualified,large sample sized,randomized controlled trials in pediatric population are needed.
其他文献
In this issue of World Journal Pediatrics,Zhao et al.address that nutrition support by nasogastric (NG) or nasojejunal(NJ) feeding has similar results in pediatric acute pancrea-titis (AP) [1].AP in children is one of the common acute abdominal diseases i
慢性肾脏病常伴心脏损害,其病机为正虚邪实,正虚以心脾肾虚为主,邪实以水湿、痰浊、气滞、浊毒为主;血瘀是慢性肾脏病心脏损害中医病机之一,且贯穿于疾病发展的始终,具体可归纳为因虚致瘀、因实致瘀、虚实夹杂致瘀.活血化瘀法在临床治疗中确有疗效,常用药物有丹参、红花等.临证治疗时重在活血化瘀,具体运用时当依据病情辨证论治.
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