患者,女,40岁,陕西丹凤县人,以“确诊慢性粒细胞白血病3年余,双手皮肤溃疡3月”入院。患者2012年初诊断为慢性粒细胞白血病,开始每日口服羟基脲1.0~3.0g至今,2014年10~11月份曾给予α-2b干扰素300万U,隔日皮下注射。2015年2月份患者双手皮肤出现粟粒大红色丘疹,双手、双足皮肤脱屑、皲裂,伴有疼痛,皮损逐渐增大,肤色呈暗红色结节, Patients, female, 40 years old, Danfeng County, Shaanxi Province, “diagnosed with chronic myeloid leukemia more than 3 years, hands and skin ulcers in March ” admission. Patients diagnosed with chronic myeloid leukemia in early 2012, began daily oral hydroxyurea 1.0 ~ 3.0g so far, from October to November 2014 had given α-2b interferon 3 million U, the next day subcutaneous injection. February 2015 patients with miliary hands on the skin appear red papules, hands, feet skin desquamation, chapped, accompanied by pain, skin lesions gradually increased, complexion was dark red nodules,