1975—1976年,我院有机化学教研室参照国外文献报道,以国产资源剑麻皂甙元为主要原料合成了降血脂甾体药去脂舒,并进行了改进合成路线、简化工艺、提高收率的研究工作。改进的合成路线和工艺,提高了收率,改善了劳动条件,比用薯芋皂甙元简便合理。后又与福州制药厂、吴县制药厂协作,进行了中试生产工艺研究。经过化学结构证明和药理、 1975-1976, our hospital organic chemistry department reference to foreign literature, domestic resources sisapogenin as the main raw material synthesis of lipid-lowering lipid-steroidal anti-liposuction, and to improve the synthesis route, to simplify the process and improve the yield research work. Improved synthetic routes and processes, improved yield, improved working conditions, than the simple and reasonable use of potato sapogenin. After the cooperation with Fuzhou Pharmaceutical Factory and Wuxian Pharmaceutical Factory, the pilot production process was studied. After chemical structure and pharmacology,