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目的 观察国产环丙沙星对婴幼儿急性菌痢的疗效.方法 用国产环沙星治疗婴幼儿急性菌剂120例,并用痢特灵+TMP治疗30例作对照;结果 国产环丙沙星治疗组总有效率比痢特灵+TMP对照组总有效率高,二者差异非常显著(P<0.001),并对治疗组46例患者进行了近期跟踪随访,至今尚无1例出现异常.结论 提示环丙沙星可用于治疗小儿急性菌痢,但在使用过程中严格掌握适应征、剂量和疗程.
Objective To observe the curative effect of domestic ciprofloxacin on acute bacillary dysentery in infants and young children.METHODS 120 cases of infants and young children were treated with homemade cyclophosphamide and 30 cases were treated with furazolidone plus TMP as control.Results The domestic ciprofloxacin The total effective rate was higher than that of furazolidone + TMP control group, with significant difference (P <0.001), and the follow-up of 46 patients in the treatment group was carried out recently, and no one had any abnormality so far. Tip ciprofloxacin can be used to treat children with acute bacillary dysentery, but strictly control the use of indications, dosage and duration of treatment.