硝普钠(化学名亚硝酰铁氰化钠)是一种强效、速效的降压药,具有扩张周围血管、降低外周阻力的作用。国外将其作为高血压危象、急性左心衰竭、心源性休克等的急救药。由于亚硝酰铁氰化钠在水中不稳定,因此,国外多制成注射用结晶或冻干粉末。为了提供临床治疗的需要和填补国内生产上的空白,我们研究了多种因素对硝普钠稳定性的影响、注射溶液的制备方法、质量标准、毒性试验及临床应用等。本实验探讨了不同浓度、温度、pH、光分解对它的影响。实 Sodium nitroprusside (chemical name of sodium nitrite sodium ferricyanide) is a potent, rapid antihypertensive drugs, with the expansion of peripheral blood vessels, reducing the role of peripheral resistance. Abroad as hypertensive crisis, acute left heart failure, cardiogenic shock and other emergency medicine. Because of the instability of water in sodium nitrocellulose, therefore, many foreign made crystal or freeze-dried powder for injection. In order to provide clinical treatment needs and to fill gaps in domestic production, we studied the effects of various factors on the stability of sodium nitroprusside, preparation methods, quality standards, toxicity tests and clinical applications of injection solutions. This experiment explored the impact of different concentrations, temperature, pH, photolysis on it. real