轮状病毒是幼儿急性腹泻的主要病因,4岁以下儿童感染该病毒后,大多都可引起腹泻。发展中国家估计每年有87万儿童死于轮状病毒感染,美国每年发生轮状病毒感染所致的腹泻有300万例,其中50万例在门诊治疗,6.7万例住院治疗(总住院天数达25万天),75例死亡。目前研制的疫苗可以保护 Rotavirus is the leading cause of acute diarrhea in young children. Most children under 4 years of age can cause diarrhea after the virus is infected. In developing countries, an estimated 870,000 children die of rotavirus infection each year. There are 3 million cases of diarrhea each year due to rotavirus infection in the United States, of which 500,000 are in outpatient settings and 67,000 are hospitalized (total hospitalization days 25 million days), 75 died. Vaccines currently developed can be protected