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目的探讨米非司酮联合甲氨蝶呤在子宫切口瘢痕妊娠中的应用效果。方法 92例子宫切口瘢痕妊娠患者,随机分为对照组和研究组,各46例。对照组进行米非司酮治疗,研究组采用米非司酮联合甲氨蝶呤治疗,观察两组患者临床效果。结果研究组住院时间、包块消失时间及不良反应指标明显优于对照组(P<0.05),研究组治疗治疗成功率达95.7%,对照组为82.6%,差异具有统计学意义(P<0.05)。结论米非司酮联合甲氨蝶呤治疗子宫切口瘢痕妊娠有效率高,并发症少,临床效果好,值得推广。
Objective To investigate the effect of mifepristone and methotrexate in the treatment of uterine incision scar pregnancy. Methods 92 cases of uterine incision scar pregnancy were randomly divided into control group and study group, 46 cases each. The control group was treated with mifepristone. The study group was treated with mifepristone combined with methotrexate, and the clinical effects of the two groups were observed. Results The hospitalization time, the disappearance of mass and the adverse reaction index in the study group were significantly better than those in the control group (P <0.05). The successful rate of the treatment group was 95.7% in the study group and 82.6% in the control group, with significant difference (P <0.05 ). Conclusion mifepristone combined with methotrexate in the treatment of uterine incision scar pregnancy, high efficiency, fewer complications, good clinical effect, it is worth promoting.