通过临床表现、胸片、肺功能及组织学检查,对36例原发性干燥综合征(Primary sjgren’s syndrome)患者的肺部表现进行了研究,发现27例(75%)的原发性干燥综合征患者,在疾病早期已有肺部(包括气管、大气道、小气道、肺实质和肺间质)受损,无1例有胸腔积液。5例经支气管肺活检,发现肺间质病变从大量淋巴细胞浸润到间质纤维化。胸片常提示有肺间质性病变,但与肺功能或组织学改变无关。最常见的呼吸系统症状为不同程度的干咳,从咽部异物感伴轻微干咳到导致呕吐的剧烈干咳,其次为运动性呼吸困难。10例两肺底可闻罗音。15例胸片可 Pulmonary manifestations in 36 patients with primary sjögren’s syndrome were studied through clinical presentation, chest radiography, lung function, and histology and found that 27 (75%) of the primary Patients with Sjögren’s syndrome have impaired lungs (including the trachea, the airways, small airways, lung parenchyma, and interstitial lungs) early in the disease, and none has pleural effusions. 5 cases of bronchial lung biopsy, interstitial lung disease found from a large number of infiltration of lymphocytes to interstitial fibrosis. Chest radiographs often indicate interstitial lung disease, but not pulmonary function or histological changes. The most common respiratory symptoms were varying degrees of dry cough, with a slight dry cough from foreign body sensation in the throat to severe dry cough leading to vomiting, followed by exercise-induced dyspnea. Ten cases can be heard at the end of lung Luo sound. 15 cases of chest can be