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于麻醉或清醒、麻痹大鼠腰膨大处观察了在记录电极局部脊髓背表面施加和向脊髓背角微电泳去甲肾上腺素NE)甘氨酸(Gly)、γ-氨基丁酸(GABA)和L-谷氨酸(L-Glu)时节段性脊髓场电位(SP)与下行性脊髓场电位(DP)的变化,结果表明,局部给药时,NE使SP与DP的N,P波波幅均明显降低;Gly、GABA和L-Glu明显降低SP与DP的N波波幅,但明显增大P的幅度。微电泳时,NE对N、P波呈减弱和增强两种效应;Gly明显削弱SP与DP的N、P渡;GABA减弱N波同时加强P披;L-Glu使N、P波幅度均显著增大,提示NE,Gly、GABA和L-Glu可能通过影响中间神经元及(或)初级传入末稍的活动,参与SP特别是DP的N,P波的形成。
Electroencephalography (NE) glycine (Gly), γ-aminobutyric acid (GABA), and γ-aminobutyric acid (GABA) were performed on the dorsal surface of the spinal cord in the anesthetized or awake, (SP) and descending spinal cord field potentials (DP) during L-Glu administration. The results showed that the amplitude of N and P waves of SP and DP were significantly increased Gly, GABA and L-Glu significantly decreased the amplitude of N wave of SP and DP, but increased the amplitude of P significantly. Microelectrophoresis, NE on the N, P wave was weakened and enhanced two kinds of effects; Gly significantly weakened SP and DP N, P cross; GABA weakened N wave while strengthening P Phi; L-Glu so N, P amplitude were significant Increase, suggesting that NE, Gly, GABA and L-Glu may participate in the formation of N and P waves of SP, especially DP by affecting the activity of interneurons and / or primary afferent endings.