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本文用酶标(ANAE)法和单克隆荧光抗体(McFAb)法研究矽肺患者的细胞免疫水平。实验结果矽肺患者ANAE、McFAb阳性率及T细胞数均比对照组有明显下降(P<0.01),说明矽肺患者细胞免疫功能减退。另外,T淋巴细胞数与矽肺病情的相关分析呈高度负相关,即随T细胞数的下降,矽肺病情加重。笔者认为外周血ANAE、McFAb阳性率及T细胞数的测定可作为研究矽肺患者细胞免疫功能的指标,亦可作为矽肺临床诊断的参考指标。
In this paper, the enzyme immunoassay (ANAE) and monoclonal antibody (McFAb) method to study the level of cellular immunity in patients with silicosis. Experimental results Silicosis patients with ANAE, McFAb positive and T cell numbers were significantly lower than the control group (P <0.01), indicating that patients with silicosis decreased cellular immune function. In addition, the correlation between T lymphocytes and silicosis was highly negative correlation, that is, with the decline of T cell number, silicosis aggravated. I believe that the determination of peripheral blood ANAE, McFAb positive rate and T cell count can be used as indicators of cellular immune function in patients with silicosis, silicosis may also be used as a reference for clinical diagnosis.