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产β-内酰胺酶细菌是目前临床常见的致病菌。近年来,随着产β-内酰胺酶细菌不断的增多,如何能有效治疗产β-内酰胺酶细菌感染已成为临床治疗的重要问题。本文综述了青霉素结合蛋白(penicillin binding proteins,PBPs)与产β-内酰胺酶细菌的耐药机制及耐药性的关系,为预防和控制产β-内酰胺酶细菌感染提供参考依据。
Producing β-lactamase bacteria is the common clinical pathogens. In recent years, with the continuous production of β-lactamase-producing bacteria, how to effectively treat β-lactamase-producing bacterial infection has become an important issue in clinical treatment. This article reviews the relationship between the mechanism of drug resistance and the drug resistance of penicillin binding proteins (PBPs) and β-lactamase-producing bacteria, and provides references for the prevention and control of β-lactamase-producing bacterial infections.