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采用免疫组化及DNA斑点杂交技术检测人咽喉部乳头状瘤及鳞状细胞癌组织中人乳头状瘤病毒（HPV）壳蛋白抗原及HPV6、11、16、18型DNA。11例乳头状瘤HPV抗原与HPVDNA阳性率均为45．5％。22例鳞状细胞癌HPV抗原阳性率22．7％，HPVDNA阳性率27.3％。乳头状瘤HPV检出率与组织学检查的结果相符。提示咽喉部乳头状瘤及鳞状细胞癌的发生、发展与HPV感染有关。
Immunohistochemistry and DNA dot blot hybridization were used to detect human papillomavirus (HPV) coat protein and HPV6, 11, 16 and 18 DNA in human throat papilloma and squamous cell carcinoma tissues. The positive rate of HPV antigen and HPV DNA in 11 cases of papilloma were 45.5%. 22 cases of squamous cell carcinoma HPV antigen positive rate of 22.7%, HPVDNA positive rate of 27.3%. Papilloma HPV detection rate and histological examination results. Tip of the throat papilloma and squamous cell carcinoma of the occurrence and development of HPV infection.