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目的分析新乡地区1796例泌尿生殖道标本的支原体培养及抗生素药物敏感试验,指导临床合理使用抗生素。方法支原体培养鉴定、药敏试剂盒购自贝瑞特公司。同时检测解脲支原体和人型支原体,并进行10种抗生素的药敏试验。数据统计采用2χ检验。结果支原体培养1596例标本中,541例解脲脲原体(Uu)阳性,阳性率为33.9%;39例人型支原体(Mh)阳性,阳性率为2.4%;解脲脲原体、人型支原体均阳性76例,阳性率为4.8%。200例正常对照组27例阳性,阳性率为13.5%。药敏结果显示,强力霉素、克拉霉素和美满霉素的抗菌活性较强。结论支原体感染以Uu为主,Uu+Mh次之,正常人泌尿生殖道支原体阳性率为13.5%。只有某些血清型感染且在达到一定浓度以上同时宿主处于多种病原体感染或免疫机制紊乱时,Uu才能致病。避免滥用抗生素引起生殖道菌群失调。临床上治疗Uu感染、Mh感染或Uu+Mh混合感染时,建议选用强力霉素、克拉霉素和美满霉素。
Objective To analyze the mycoplasma culture and antibiotic susceptibility testing of 1796 genitourinary tract specimens in Xinxiang area to guide the rational use of antibiotics. Methods Mycoplasma culture identification, drug sensitivity kit purchased from Barrett company. Meanwhile, Ureaplasma urealyticum and Mycoplasma hominis were detected, and drug susceptibility tests of 10 antibiotics were conducted. Data statistics using 2χ test. Results Among 1596 mycoplasma samples, 541 cases were positive for Uu, the positive rate was 33.9%; 39 cases were positive for Mh, the positive rate was 2.4%; Ureaplasma urealyticum, human type Mycoplasma were positive in 76 cases, the positive rate was 4.8%. In the 200 normal control group, 27 cases were positive, the positive rate was 13.5%. Drug sensitivity results show that, doxycycline, clarithromycin and minocycline antibacterial activity. Conclusion Mycoplasma infection is mainly Uu, followed by Uu + Mh. The positive rate of genitourinary tract mycoplasma in normal people is 13.5%. Only certain serotypes and above a certain concentration of host while a host of pathogens in a variety of infections or immune disorders, Uu can pathogenic. Avoid abuse of antibiotics cause reproductive tract flora disorders. Clinical treatment of Uu infection, Mh infection or mixed infection of Uu + Mh, the proposed selection of doxycycline, clarithromycin and minocycline.