乙磺酰基乙腈是制备超高效磺酰脲类除草剂砜嘧磺隆的关健中间体之一。目前相关文献报道乙磺酰基乙腈是通过将硫醚类化合物乙硫基乙腈氧化为砜而制得,其方法主要是与氧化剂的选择不同而形成路线不同,主要有以下几种方法:1)以二氯甲烷作溶剂,间氯过氧苯甲酸作氧化剂;2)以醋酸作溶剂,水合过硼酸钠作氧化剂;3)以醋酸作溶剂,过氧化氢作氧化剂;4)以硝酸、臭氧、二氧化氮等作为氧化剂。 Ethanesulfonylacetonitrile is one of the key intermediates for the preparation of the super-efficient sulfonylurea herbicidal rimsulfuron-methyl. At present, it has been reported in the literature that ethanesulfonylacetonitrile is prepared by the oxidation of the thioether ethylthioacetonitrile to sulfone. The method is mainly based on the difference in the choice of the oxidant and leads to different routes. There are mainly the following methods: 1) Methylene chloride as a solvent, m-chloroperbenzoic acid as an oxidant; 2) acetic acid as a solvent, hydrated sodium perborate as an oxidizing agent; 3) acetic acid as a solvent, hydrogen peroxide as an oxidizing agent; Nitrogen oxide as an oxidizer.