基因芯片又称DNA芯片或微阵列,为近些年发展起来的一项前沿技术—生物芯片中的一种(广义的生物芯片还包括蛋白芯片、组织芯片等)。基因表达芯片是用于基因表达谱研究的一种应用型基因芯片。本文主要综述了基因表达芯片在炎症、氧化低密度脂蛋白、感染、同型半胱氨酸、血流动力学、吸烟等与动脉粥样硬化关系上的研究概况。 Gene chips, also known as DNA chips or microarrays, are one of the leading technologies developed in recent years - one of biochips (generalized biochips also include protein chips, tissue chips, etc.). Gene expression chip is an applied gene chip for gene expression profiling. This review summarizes the research progress of gene expression microarray in relation to atherosclerosis such as inflammation, oxidized low density lipoprotein, infection, homocysteine, hemodynamics, smoking and so on.