论文部分内容阅读
本实验用Wistar大鼠复制烧伤模型,应用中药石膏治疗,观察烧伤及其修复过程中血液中T淋巴细胞及腹腔巨噬细胞功能的变化。结果表明:烧伤大鼠血中T淋巴细胞数和功能明显低于对照组(对照组T淋巴细胞数为52.19±2.82%,烧伤组值为36.00±3.01%,经统计学处理P<0.01);对照组腹腔巨噬细胞吞噬率为75.13±2.50%,而烧伤组值为66.25±1.58%(P<0.01)。应用石膏后大鼠烧伤创面明显恢复,且血中T淋巴细胞数及功能亦明显增高(46.19±3.53%),腹腔巨噬细胞吞噬率亦接近对照组值(73.75±2.99%)。因此,作者推论:中药石膏治疗烧伤的作用可能与机体细胞免疫功能增强有关。
In this experiment, Wistar rats were used to replicate the burn model, and plaster was used to treat the changes of T lymphocytes and peritoneal macrophages in the blood during burns and their repair. The results showed that the number and function of T lymphocytes in the blood of burned rats were significantly lower than those in the control group (the number of T lymphocytes in the control group was 52.19±2.82% and the value in the burn group was 36.00±3.01%, P<0.01 by statistical analysis); The phagocytic rate of peritoneal macrophages was 75.13±2.50% in the control group, and 66.25±1.58% in the burn group (P<0.01). After the application of plaster, the burn wounds of rats recovered obviously, and the number and function of T lymphocytes in blood were also significantly increased (46.19±3.53%), and the phagocytic rate of peritoneal macrophages was also close to that of the control group (73.75±2.99%). Therefore, the authors concluded that the effect of gypsum plaster on burns may be related to the enhancement of cellular immune function.