本文报告二例因口服醋唑磺胺(Diamox)引起急性肾功能衰竭。一例经治疗痊愈,另一例救治无效死亡,尸检发现肾曲管、小管及肾盂内均有大量类似于磺胺的结晶。结合文献对致病机理进行了讨论,同时提出临床使用该药时需注意的几点意见。 This article reports two cases of acute renal failure caused by oral administration of azamil (Diamox). One case was cured, another died of treatment ineffective autopsy found that a large number of renal tubules and tubules are similar to sulfonamide crystals. The pathogenic mechanism was discussed in combination with the literature, and some opinions that should be paid attention to when using this medicine in clinical practice were put forward.