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大骨节病是一种至今原因不明的严重地方病,主要病理变化是软骨的变性和坏死。近年来生物化学方面的研究显示患者体内生化改变的主要特点是组织细胞功能代谢紊乱,代谢调解系统变化及软骨组织和胶原组织代谢的变
Kashin-Beck disease is a serious endemic disease whose cause is unknown so far. The main pathological changes are degeneration and necrosis of cartilage. In recent years, biochemical studies have shown that the main characteristics of patients with biochemical changes in tissue and cell metabolism disorders, changes in metabolic regulation system and changes in cartilage tissue and collagen metabolism