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鼻咽癌是我国南部,特别是两广地区高发的一种恶性肿瘤。由于其解剖学特点及生物学行为决定了其不能行常规手术治疗,故放射治疗成为治疗鼻咽癌的主要手段。但初诊时晚期患者占约70%以上,单纯放疗后有一半以上的患者将出现复发和(或)转移,并导致死亡,因此,对于晚期患者放化疗结合已成为主要治疗手段。放化疗联合的协同作用可能是某些药物(如DDP等)影响了亚致死或潜在致死性损伤后的细胞
Nasopharyngeal carcinoma is a malignant tumor in southern China, especially in Guangdong and Guangxi. Because of its anatomical characteristics and biological behavior determines that it can not be routine surgical treatment, so radiation therapy has become the main means of treatment of nasopharyngeal carcinoma. However, about 70% of patients are newly diagnosed late stage, more than half of patients after radiotherapy alone will have recurrence and / or metastasis, leading to death. Therefore, the combination of radiotherapy and chemotherapy has become the main treatment for advanced patients. The synergistic effect of chemoradiation may be that certain drugs (such as DDP) affect the cells after sublethal or potentially lethal injury