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目的：观察清开灵治疗流行性腮腺炎的临床疗效。方法选取2013年12月-2014年12月门诊收治流行性腮腺炎患者60例，随机分为观察组和对照组各30例。对照组予利巴韦林治疗，观察组予清开灵颗粒口服，2组疗程均为3~7d。比较2组临床效果。结果观察组总有效率80.0%明显高于对照组的66.7%（P ＜0.05）。观察组平均退热时间及平均腮肿消退时间均短于对照组，差异均有统计学意义（P ＜0.05）。2组均无严重不良反应发生。结论清开灵颗粒剂口服治疗流行性腮腺炎，显效快，疗效显著，不良反应少。值得临床推广应用。“,”Objective To observe the clinical effects of treatment of Qingkailing in the treatment of mumps. Methods From December 2013 to December 2014,60 cases of patients with mumps were randomly divided into observation group and control group,each of 30 cases. The control group was given virazole intramuscular injection or intravenous drip. The observa-tion group was given Qingkailing oral. Both groups were treated for 3 ~ 7d. The clinical effect of 2 groups were compared. Re-sults The total effective rate of observation group was 80. 0% ,which was higher than 66. 7% of control group,the difference was statistically significant(P < 0. 05). The average defervescence time and the mean fading time of parotid gland swelling in the observation group was less than those of the control group,the difference was statistically significant(P < 0. 05). Conclu-sion The effect of Qingkailing is remarkable in the treatment of mumps,with less adverse reactions,which is worthy of clinical popularization and application.