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哈佛大学研究小组成员在报告中指出,一种抗心肌肌球蛋白的单克隆抗体能够极准确地显示心肌梗塞的大小。该研究小组指出,在一系列的实验研究中,实验狗冠状动脉梗塞3小时后用抗肌球蛋白放射免疫闪烁照相所摄的影象,实际上与尸体剖检时用四唑蓝染色所显示的心肌梗塞的大小完全相同。相反,通常用于检查心肌梗塞大小的焦磷酸盐显影比实际坏死区平均大1.5倍。放射学副教授Ban An Khaw报告说,根据这些发现,他们作了初步临床试验,用抗肌球蛋白估计梗塞大小及其对预后的价值,证明这种估计大小的方法是预示心肌梗塞并发症的“有效的指征”。
Harvard University research team members pointed out in the report that a monoclonal antibody against cardiac myosin can be very accurately show the size of myocardial infarction. The team noted that in a series of experimental studies, the images taken with anti-myosin radioimmunoscintigraphy three hours after the experimental dog’s coronary artery infarction were in fact shown to be stained with tetrazolium blue at necropsy The size of the myocardial infarction exactly the same. In contrast, pyrophosphate imaging, which is commonly used to check myocardial infarct size, is on average 1.5 times larger than the actual necrotic area. Ban An Khaw, an associate professor of radiology, reported that based on these findings, they conducted a preliminary clinical trial to assess infarct size and its value in prognosis with antimyosin, a proven method of predicting myocardial infarction complications “ Valid indication. ”