[目的]探讨后腹腔镜下肾上腺肿瘤切除手术的疗效和安全性。[方法]后腹腔镜下肾上腺肿瘤切除手术治疗21例。[结果]21例均完成手术,手术时间60～190min,术中出血量约50～200ml。术后住院天数平均5.1d,切口愈合良好。[结论]后腹腔镜肾上腺肿瘤切除手术不仅能够避免对腹腔内脏器的扰动、损伤,同时具有创伤小、康复快、安全、住院时间短等优点。 [Objective] To investigate the efficacy and safety of retroperitoneoscopic adrenalectomy. [Methods] 21 cases underwent laparoscopic adrenalectomy. [Results] All the 21 cases completed the operation, the operation time was 60-190min, and the intraoperative blood loss was about 50-200ml. The average length of hospital stay after surgery was 5.1 days, and the incision healed well. [Conclusion] The retroperitoneoscopic adrenal tumor resection can not only avoid the disturbance and injury to the internal organs of the abdominal cavity, but also has the advantages of less trauma, quicker recovery, safety, and shorter hospital stay.