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目的 探讨双径路动脉灌注化疗防治肿瘤局部复发及肝转移的价值。方法 全组２５ 例，在切除胃肠道肿瘤的同时，应用微泵技术，最大耐受剂量，对原肿瘤供血区域的动脉主干插管置泵灌注化疗，同时进行预防肝转移的肝动脉插管置泵化疗。结果 经临床观察和随访１０～２４ 个月，随访期病例全部存活，均未发现肿瘤局部复发和肝转移，胃肠道肿瘤主要标志物放射免疫测定２２／２３ 例在正常范围。结论 双径路动脉置泵灌注化疗防治中晚期胃肠道肿瘤局部复发和肝转移效果良好，且安全易行
Objective To investigate the value of dual-channel arterial infusion chemotherapy in preventing and treating local tumor recurrence and hepatic metastasis. Methods In the whole group of 25 patients, gastrointestinal tumors were resected at the same time, micro-pump technology was applied, and the maximum tolerated dose was used. The arterial trunk of the original tumor blood supply area was intubated with pump-infusion chemotherapy, and hepatic artery catheterization for preventing liver metastases was performed at the same time. Pump chemotherapy. Results After clinical observation and follow-up of 10 to 24 months, all cases survived during the follow-up period. Local tumor recurrence and hepatic metastasis were not found. Radioimmunoassay was the main marker for gastrointestinal cancer. 22/23 cases were in the normal range. Conclusion Dual-pathway arterial pump perfusion chemotherapy is effective and safe for the prevention and treatment of local recurrence and hepatic metastasis of middle-late gastrointestinal tumors.