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目的:评价头孢曲松与利福霉素联用治疗儿童化脓性脑膜炎患者的临床疗效。方法:选取2014年3月—2015年3月间收治的儿童化脓性脑膜炎患者90例,将其分为观察组和对照组,每组45例;对照组患者给予头孢曲松治疗,观察组患者则给予头孢曲松与利福霉素联用治疗,比较和评价两组患者治疗后的总有效率、外周白细胞计数复常时间和外周脑脊液复常时间。结果:观察组患儿治疗后的总有效率优于对照组(P<0.05),外周脑脊液和外周白细胞计数的复常时间优于对照组(P<0.05)。结论:采用头孢曲松与利福霉素治疗化脓性脑膜炎患儿,临床效果极为理想,安全性高。
Objective: To evaluate the clinical efficacy of ceftriaxone and rifamycin in the treatment of children with purulent meningitis. Methods: Totally 90 children with purulent meningitis were selected from March 2014 to March 2015. They were divided into observation group and control group, with 45 cases in each group. Patients in the control group were treated with ceftriaxone, and the observation group Patients were given ceftriaxone and rifamycin combined treatment, comparison and evaluation of the two groups of patients after treatment, total effective rate, peripheral leukocyte count time and peripheral cerebrospinal fluid recanalization time. Results: The total effective rate of observation group was better than that of control group (P <0.05). The recovery time of peripheral blood cerebrospinal fluid (CSF) and peripheral white blood cell count was better than that of control group (P <0.05). Conclusion: The treatment of patients with purulent meningitis by ceftriaxone and rifamycin has the best clinical effect and high safety.