中国医学科学协和医院张乃峥等经过五年研究,建立了临床常用的抗核抗体测定方法11种。均经国际标准血清验证,所需抗原均为该院内科免疫组自己制备。找出了国内自己的参考阳性血清。经临床应用,具体结果如下:1、抗双链DNA抗体(抗DS-DNA抗体,用短膜虫免疫荧光法):CTD(结缔组织病)174人中阳性19％, Chinese Academy of Medical Sciences and other hospitals Zhang Naizheng after five years of research, the establishment of clinical commonly used anti-nuclear antibody assay 11 kinds. After the international standard of serum validation, the required antigens were prepared for the hospital’s internal medicine group. Identify the domestic own reference positive serum. Clinical application, the specific results are as follows: 1, anti-double-stranded DNA antibody (anti-DS-DNA antibody, using short film worm immunofluorescence): CTD (connective tissue disease) 174 were positive 19%