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目的观察乳腺癌针吸细胞学与组织学诊断符合情况以及相应激素受体表达的临床意义。方法将本院2006年-2011年间进行乳腺癌肿块针吸细胞学及行手术后病理组织学检查确诊患者281例,从诊断符合情况、病变的病理类型、激素受体表达情况等方面进行对比分析。结果两种方法检测乳腺癌的符合率较高,对应激素受体表达有显著的差异性。结论①乳腺癌针吸细胞学与组织学病理诊断符合率达97.8%。②恶性病变中浸润性导管癌居多占63.0%。③激素受体测定中CerbB-2过度表达差异性显著。④CerbB-2阳性是乳腺癌患者愈后差的指标,ER、PR阳性是愈后好的指标。
Objective To observe the coincidence of needle cytology and histological diagnosis of breast cancer and the clinical significance of corresponding hormone receptor expression. Methods A total of 281 patients diagnosed with needle-aspiration cytology of breast cancer and histopathological examination after surgery from 2006 to 2011 were compared and analyzed from the aspects of diagnosis conformity, pathological types of disease, and expression of hormone receptors. . Results The coincidence rate of the two methods for detecting breast cancer was higher, and there was a significant difference in the expression of hormone receptors. Conclusion 1 The coincidence rate of needle cytology and histological diagnosis of breast cancer is 97.8%. 2 Invasive ductal carcinoma accounted for 63.0% of malignant lesions. 3 CerbB-2 overexpression was significantly different in hormone receptor assays. 4CerbB-2 positive is an indicator of worsening of breast cancer patients. Positive ER and PR are better indicators.