论文部分内容阅读
目的探讨巴氯芬治疗痉挛型小儿脑性瘫痪的效果。方法对确诊的５０例患儿按年龄给药，剂量为每日４０～７５ｍｇ，逐渐增量，１０～１５ ｄ为１疗程，分级标准采用改良的Ａｓｈｕｏｒｔｈ评分法。结果显效３例，有效１２例，好转２０例，总有效为３５例，总有效率７０％。并且１～３岁与４～６岁两年龄组间存在显著性差异（Ｐ＜０．００１）。结论巴氯芬是目前降低痉挛型脑瘫患儿肌张力最有效的方法之一，且年龄越小，效果越好，同时应严密观察其副作用。
Objective To investigate the effect of baclofen in treating spastic cerebral palsy in children. Methods Fifty cases were diagnosed by age. The dosage was 40 ~ 75mg per day, gradually increasing, and 10 ~ 15 days as a course of treatment. The graded standard was modified Ashurth’s score method. The results were markedly effective in 3 cases, effective in 12 cases, improved in 20 cases, the total effective for 35 cases, the total effective rate was 70%. There was also a significant difference between the two age groups of 1 ~ 3 years and 4 ~ 6 years (P <0.001). Conclusions Baclofen is one of the most effective ways to reduce the muscle tone of children with spastic cerebral palsy. The younger the effect is, the better the side effects of baclofen should be observed.