有些药物,如利多卡因(lignocaine)对控制严重心律失常很有效。最近报道一新化合物E-3753,其化学名为lH-咪唑-2-羟甲基α-(3-三氟甲基苯基)-α-氧-甲基-(3-特丁基-胺基丙基)-2-醇。该药也具有较好的抗心律失常作用。由Delpon等人研究的E-3753的电生理性质表明,该化合物在缓解由毒毛旋花子甙C(oubain)引起的室性心律失常与利多卡因同样有效,控制由机械性损伤引起的心律失 Some drugs, such as lignocaine, are effective in controlling severe arrhythmias. Recently a new compound E-3753 has been reported which has the chemical name lH- imidazole-2-hydroxymethyl a- (3-trifluoromethylphenyl) -alpha-oxy- methyl- Propyl) -2-ol. The drug also has good anti-arrhythmic effect. The electrophysiological properties of E-3753, by Delpon et al., Demonstrate that the compound is also as effective as lidocaine in alleviating ventricular arrhythmias induced by oubain and controls heart rhythms caused by mechanical injury Lost