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目的 探讨小儿胃食管反流对肺功能影响。方法 以胃钡餐及胃镜确诊为胃食管反流的 2 0例小儿作为观察对象。用婴幼儿肺功能仪进行潮气吸气峰流速 (PTIF)、潮气呼气峰流速 (PTEF)、潮气呼气中期流速 /潮气吸气中期流速 (ME/MI)、呼出 75 %潮气量时的呼气流速 /潮气呼气峰流速 (2 5 /PF)等肺功能指标检测 ,其中 >3岁者尚须运用Spirostrac肺功能仪进行第 1秒最大呼出量实测值 /预计值百分比 (FEV1% )、第 1秒最大呼出率 (FEV1/FVC % )检测。结果 胃食管反流的小儿均存在不同程度的肺功能损害 ,其中潮气容量环PTIF PTEF(35 .9± 35 .1)、ME/MI(0 .73± 0 .17)、2 5 /PE(0 .6 6± 0 .13)较正常健康儿童组PTIF PTEF(2 2 .5± 4 .9)、ME/MI(0 .98± 0 .0 4 )、2 5 /PF(0 .77± 0 .0 7)有显著差异。 2 0例中 ,9例 >3岁儿童 ,其FEV1% (70 .8± 5 .5 )、FEV1/FVC % (79.1± 9.6 )较健康对照组FEV1% (90 .8± 4 .8)、FEV1/FVC % (92 .8± 5 .5 )明显降低。结论 胃食管反流的小儿存在气道阻塞性改变
Objective To investigate the effect of gastroesophageal reflux on pulmonary function in children. Methods 20 cases of children diagnosed as gastroesophageal reflux by gastric barium meal and endoscopy were selected as observation objects. The PTIF, PTEF, ME / MI, and 75% of the tidal volume exhaled were recorded using an infant’s pulmonary function meter. (2 5 / PF) and other lung function tests, of which> 3-year-old Spirostrac pulmonary function meter still have to take the first second maximum expired measured value / predicted percentage (FEV1%), 1 second maximum exhalation rate (FEV1 / FVC%) detection. Results Gastroesophageal reflux occurred in children with varying degrees of pulmonary dysfunction, including PTIF PTEF (35.9 ± 35.1), ME / MI (0.73 ± 0.17), 25 / PE (P> 0.05), ME / MI (0 .98 ± 0. 04), 25 / PF (0 .77 ± 0. 0 .0 7) There are significant differences. Among 20 cases, FEV1 / FVC% (79.1 ± 9.6) FEV1% and FV1% (90.8 ± 4.88) in FEV1 / FVC were significantly higher than those in healthy controls FEV1 / FVC% (92 .8 ± 5 .5) was significantly lower. Conclusion There is airway obstruction in children with gastroesophageal reflux