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目的探讨贝那普利/氨氯地平片与氨氯地平单药治疗轻中度原发性高血压的疗效和安全性。方法选取我院2014年1月~2016年1月收治的原发性高血压患者100例为研究对象,将其分为观察组和对照组,观察组给予贝那普利/氨氯地平,对照组给予氨氯地平片;比较两组患者疗效和不良反应。结果对比两组患者的治疗总有效率、血压相关指标、不良反应发生率,观察组明显更佳,差异有统计学意义(P<0.05)。结论贝那普利/氨氯地平片较氨氯地平片治疗中轻度原发性高血压更有效、安全,且无严重不良反应。
Objective To investigate the efficacy and safety of benazepril / amlodipine and amlodipine in the treatment of mild to moderate essential hypertension. Methods A total of 100 patients with essential hypertension treated in our hospital from January 2014 to January 2016 were selected as study subjects and divided into observation group and control group. The observation group was given benazepril / amlodipine. The control group Group given amlodipine tablets; efficacy and adverse reactions were compared between the two groups. Results Compared with the two groups, the total effective rate of treatment, blood pressure related indicators, the incidence of adverse reactions, the observation group was significantly better, the difference was statistically significant (P <0.05). Conclusion benazepril / amlodipine is more effective and safe than amlodipine in the treatment of mild essential hypertension, and no serious adverse reactions.