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为探索HBsAg携带者（下称携带者）有效的管理方法，从1984～1989年对某工厂的222例HBsAg阳性者进行了追踪研究，总结如下的综合管理措施：①宣传教育，在人群中普及乙肝防治知识；②建立携带者个例卡片，定期访视，每年复查，从动态观察中掌握携带者的临床与血清学转归；③建立携带者家庭成员卡片，开展家庭内传播情况的调查；④保护易感者，乙肝疫苗问世使保护易感者由被动变为自动免疫；⑤治疗携带者，主要治疗对象是临床转归成急性乙肝和慢性肝病者以及那部分HBeAg阳性的携带者。通过上述综合管理措施，增加了携带者的阴转，减少了人群中乙肝的发病，有效保护了易感人群。
In order to explore an effective management method for HBsAg carriers (hereinafter referred to as carriers), 222 HBsAg positive individuals from a factory were traced from 1984 to 1989, and the following comprehensive management measures were summarized: ① publicity and education, popularized in the population Hepatitis B prevention and control knowledge; ②Create a carrier card, regular visits, annual review, from the dynamic observation of carrier clinical and serological outcomes; ③Carrier family member card, to carry out the investigation of the spread of family communication; ④ protection of susceptible, Hepatitis B vaccine came out to protect the susceptible by passive into autoimmune; ⑤ treatment of carriers, the main treatment of patients is clinically converted to acute hepatitis B and chronic liver disease and that part of HBeAg-positive carriers. Through the above comprehensive management measures, it increases the vagaries of carriers, reduces the incidence of hepatitis B in the population and effectively protects the susceptible population.