论文部分内容阅读
目的:研究不同剂量的缬沙坦治疗糖尿病肾病(DN)合并高血压的临床疗效。方法:回顾性分析我院收治的45例糖尿病肾病合并高血压患者的临床资料。结果:试验组在收缩压(SBP)、24h蛋白尿、血浆白蛋白指标方面,治疗前和治疗后比较差异有显著差异(P<0.05),组间比较160m g缬沙坦治疗组各项指标明显优于另外2组(P<0.05);对照组患者治疗前后各项指标无显著性差异(P>0.05),而缬沙坦治疗前后肾功能指标无明显变化。结论:缬沙坦对具有良好的降压,降低蛋白尿,维持血浆白蛋白和清除血清肌酐的作用。
Objective: To study the clinical effects of different dosages of valsartan in the treatment of diabetic nephropathy (DN) complicated with hypertension. Methods: The clinical data of 45 patients with diabetic nephropathy complicated with hypertension treated in our hospital were retrospectively analyzed. Results: There were significant differences in SBP, 24h proteinuria and plasma albumin levels before and after treatment in the experimental group (P <0.05). Compared with 160m g valsartan treatment group (P <0.05). There was no significant difference between the two groups before and after treatment (P> 0.05), but there was no significant change of renal function before and after valsartan treatment. Conclusion: Valsartan has good antihypertensive effect, reduce proteinuria, maintain plasma albumin and clear serum creatinine.