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自1973年以来,有关生化指标对矽肺诊断的意义相继有所报导。我们对各期矽肺血矽、铜兰蛋白和尿羟脯氨酸也曾做过初步的观察,认为上述二项指标随病期的进展而增加。但目前国内报导的 O—Ⅰ期生化指标的数值各有不同。我们对 O—Ⅰ期进行了分组观察,并将未治疗过的与治疗过的矽肺病人进行了对比,以判定铜兰蛋白和尿羟脯氨酸两项生化指标在早期诊断中的意义。对象和方法一、对象本文测定了273例,其中 O-Ⅰ、SⅠ、SⅡ、SⅢ未经治疗的病人共170例,治疗过的48例,对照组(冷加工车间不接尘工人)34例,电焊工21例.均为男性、25岁以上
Since 1973, the biochemical indicators of the significance of the diagnosis of silicosis have been reported. We have also made preliminary observations on various stages of silicosis, ceruloplasmin and urinary hydroxyproline, suggesting that the above two indicators increase with the progression of disease. However, the current national reports of O-Ⅰ biochemical indicators have different values. We observed the O-Ⅰ phase, and compared untreated and treated silicosis patients to determine the significance of the two biochemical markers of ceruloplasmin and urinary hydroxyproline in the early diagnosis. Subjects and methods First, the object This paper measured 273 cases, of which 170 cases of untreated O-Ⅰ, SⅠ, SⅡ, SⅢ, 48 cases of treatment, control group (cold workshop without dust workers) 21 welders were male, over 25 years of age