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目的探讨新生儿惊厥的病因、临床表现及治疗方法,为新生儿危重病的抢救与紧急处理积累经验。方法采用回顾分析法,查阅六安市金安区妇幼保健院2008年6月-2011年7月107例惊厥新生儿收治和治疗的临床病例资料,并采用Excel软件进行统计处理。结果缺血缺氧性脑病(hypoxic-ischemic encephalopathy,HIE)、颅内出血是新生儿惊厥的主要病因,其中HIE、颅内出血多在出生后3 d内发病,而低钙血症、感染多在出生3 d后发病,遗传代谢性疾病则出现时间不确定,治疗后惊厥仍反复出现是其特点。结论掌握新生儿惊厥的常见病因与临床表现及其与发病日龄之间的关系可以提高治愈率,改善新生儿预后情况。
Objective To explore the etiology, clinical manifestations and treatment of neonatal convulsions and to accumulate experience for the emergency treatment and rescue of critically ill newborns. Methods The retrospective analysis method was used to refer to clinical data of 107 cases of neonatal seizures and treatment of convulsions from June 2008 to July 2011 in Jin’an District Maternal and Child Health Hospital of Lu’an City and the statistical software was used for the statistical treatment. Results Hypoxic-ischemic encephalopathy (HIE) and intracranial hemorrhage were the main causes of neonatal seizures. Among them, HIE and intracranial hemorrhage mostly occurred within 3 days after birth, while hypocalcemia and infection were mostly at birth 3 d after the onset of genetic metabolic diseases appear uncertain time, the recurrence of convulsions after treatment is its characteristic. Conclusion To grasp the common etiology and clinical manifestations of neonatal convulsion and its relationship with the age of onset can improve the cure rate and improve the prognosis of neonates.