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目的:本文通过奥美拉唑与泮托拉唑治疗消化性溃疡的临床疗效及安全性对照进行分析探讨。方法:选择我院自2012年5月至2013年5月期间收治消化性溃疡患者100例,并将其随机分为对照组(n=50)和观察组(n=50),本组50患者均接受克拉霉素缓释片和阿莫西林胶囊,给予对照组患者接受奥美拉唑治疗,给予观察组患者接受泮托拉唑治疗,对两组患者治疗后的临床效果进行比较。结果:两组患者治疗后,对照组患者治疗的总有效率为98%,对照组患者治疗总有效率为94%,对照组患者治疗后不良反应发生率为14%,观察组患者治疗后不良反应发生率16%,组间无明显差异,不具有统计学意义(P〉0.05)。结论:奥美拉唑与泮托拉唑的治疗效果相似,治疗胃溃疡效果显著,可以有效的改善患者的肠道症状,并根据患者的不同进行适当的选择。
Objective: In this paper, the clinical efficacy and safety of omeprazole and pantoprazole in the treatment of peptic ulcer were analyzed and discussed. Methods: One hundred patients with peptic ulcer admitted to our hospital from May 2012 to May 2013 were randomly divided into control group (n = 50) and observation group (n = 50). 50 patients Were treated with clarithromycin sustained-release tablets and amoxicillin capsules. The patients in the control group received omeprazole and the patients in the observation group received pantoprazole. The clinical effects of the two groups were compared. Results: After treatment, the total effective rate of the control group was 98%, that of the control group was 94%, and that of the control group was 14% after the treatment. The adverse reactions of the observation group after treatment Response rate was 16%, no significant difference between groups, not statistically significant (P> 0.05). CONCLUSION: Omeprazole and pantoprazole have similar therapeutic effects. The treatment of gastric ulcer is effective. It can effectively improve the intestinal symptoms of patients and make appropriate choice according to patients.