本文从分子生物学角度讨论癌变机理。癌变机理的内容可用DDS三个字母概括,第一个D代表基因损伤(Damage of Gene),第二个D代表去阻及去分化(Derepression and Dedifferentiation),S代表选择(Selection),即致癌过程大致经过基因损伤,去阻及去分化与选择几个阶段。基因的损伤常由外因诱发,故先从致癌的外因与内因说 This article discusses the mechanism of carcinogenesis from the perspective of molecular biology. The content of the mechanism of carcinogenesis can be summarized by three letters of DDS, the first D represents Damage of Gene, the second D represents derepression and deferentiation, S represents Selection, After roughly through genetic damage, de-blocking and de-differentiation and selection of several stages. Gene damage is often induced by external causes, so first from the carcinogenic external and internal causes