允许性高碳酸血症作为一种肺保护性通气策略，具有多器官保护作用。研究表明，允许性高碳酸血症对脑功能存在保护作用，文章拟从允许性高碳酸血症对脑血流、颅内压、脑血流自动调节功能、脑血管反应性及脑氧代谢等多方面的作用进行综述，为允许性高碳酸血症的后期研究及临床麻醉期间的应用提供理论依据。“,”Permissive hypercapnia, as a lung protective ventilation strategy, has multiple organ protective effects. Studies have shown that permissive hypercapnia has protective effects on brain function. This article reviews the effects of permissive hypercapnia on cerebral blood flow, intracranial pressure, cerebral blood flow self-regulation, cerebrovascular reactivity and cerebral oxygen metabolism, so as to provide theoretical basis for the later research of permissive hypercapnia and its application during clinical anesthesia.