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目的 分析比较铜绿假单胞菌 (PA)医院感染与外环境中PA的相关性 ,以了解医院感染病原菌来源。方法 比较PA医院感染株、社区感染株、环境株的耐药谱以及随机引物扩增多态性基因分型 (RAPD)型别之间的差异 ,判断三者之间的相关性。结果 收集PA医院感染株 18株 ,社区感染株 17株 ;1190份环境样中共分离到PA2 1株 ,环境分离率为 1 76 %。耐药谱与RAPD分型表明医院感染株与社区感染株、环境株之间无明显相关性。结论 铜绿假单胞菌医院感染可能以内源性途径为主
Objective To compare and analyze the correlation between Pseudomonas aeruginosa (PA) nosocomial infection and peripheral PA in order to understand the source of nosocomial infection pathogens. Methods To compare the differences of drug resistance spectrum between PA hospital infection strains, community infection strains and environmental strains and random amplified polymorphic DNA (RAPD) genotypes, and to determine the correlation between them. Results 18 strains of PA hospital infection and 17 strains of community infection were collected. Among 1190 environmental samples, 1 strain of PA2 was isolated with an environmental isolation rate of 1 76%. Resistance spectrum and RAPD typing showed that there was no significant correlation between nosocomial and community infection and environmental strains. Conclusion Pseudomonas aeruginosa nosocomial infection may be mainly endogenous