设计并制作了一套工作频率为０．５ＭＨｚ的射频组织间透热治疗系统。由于将肿瘤组织均匀地加热到治疗温度（如４２℃左右）并持续一段时间，是透热疗法的关键和难点，因而精确的温度测量，准确的温度控制以及均匀的温度分布是本文所追求的目标。本文除研制了足以使肿瘤组织加热升温的射频功率源外，还研制了可靠的以ＰＮ结作传感器的测温系统和以变容二极管作控制单元的控温电路，具有温度多路采集、单方式显示和单通道监控的模拟实时控制方法，并且利用脑肿瘤的生物模拟材料进行了实验，证明本系统工作正常，性能可靠。 A radiofrequency tissue diathermy treatment system operating at a frequency of 0.5 MHz was designed and fabricated. Because the tumor tissue is evenly heated to the treatment temperature (such as about 42 °C) and continued for a period of time, it is the key and difficult point of diathermy. Therefore, accurate temperature measurement, accurate temperature control and uniform temperature distribution are pursued by this article. aims. In addition to developing a radio frequency power source sufficient to raise the temperature of tumor tissue, a reliable temperature measurement system with a PN junction sensor and a temperature control circuit with a varactor as a control unit have been developed. The analog real-time control method of the mode display and the single-channel monitoring, and the use of biological simulation materials of brain tumors have been carried out experiments to prove that the system is working normally and the performance is reliable.