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目的:探讨普拉格雷与氯吡格雷在对冠心病治疗过程中所得到临床效果。方法:选择2013年9月-2014年6月间我院曾接收的冠心病患者92例,将这些患者分别以随机方法分为观察组与对照组,对照组中患者选择氯吡格雷进行治疗,观察组中患者选择普拉格雷进行治疗,观察其临床效果。结果:在经过治疗之后,观察两组患者临床有效率,对照组中患者所得到临床总有效率为78.3%,观察组中患者所取得临床总有效率为93.5%;对两组患者冠心病控制时间进行观察,观察组中患者所需要时间明显短于对照组;观察两组患者不良反应发生情况,在进行治疗过程中以及治疗结束之后,观察组中患者不良反应为6.5%,对照组中为17.4%,两组之间存在明显差异。结论:普拉格雷与氯吡格雷在治疗冠心病方面为两种常用药物,并且均能够得到一定临床效果,但普拉格雷所得到临床有效率要高于氯吡格雷,并且其能够更快对患者症状进行控制,并且不良反应要低于氯吡格雷,在临床上尽量选择普拉格雷对冠心病进行治疗。
Objective: To investigate the clinical effect of prasugrel and clopidogrel in the treatment of coronary heart disease. Methods: From September 2013 to June 2014, 92 patients with coronary heart disease who received in our hospital were randomly divided into observation group and control group, patients in control group were treated with clopidogrel, Patients in the observation group were treated with prasugrel and their clinical effects were observed. Results: After treatment, the clinical efficiency of the two groups were observed. The total effective rate of the patients in the control group was 78.3%. The total effective rate of the patients in the observation group was 93.5%. The control of coronary heart disease Time was observed in the observation group, the time required for patients was significantly shorter than the control group; observed two groups of patients with adverse reactions, during the course of treatment and after the end of treatment, adverse reactions in the observation group was 6.5% in the control group 17.4%, there are significant differences between the two groups. CONCLUSIONS: Prasugrel and clopidogrel are two commonly used drugs in the treatment of coronary heart disease and are clinically effective, but prasugrel is clinically more effective than clopidogrel and is more potent The patient’s symptoms were controlled and the side effects were lower than that of clopidogrel. Clinicians should try their best to treat prasugrel coronary heart disease.