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目的分析终末期肾病患者维持性血液透析(MHD)中发生相关高血压(IDH)常见易患因素。方法肾内科血液净化中心接受MHD治疗的终末期肾病患者191例,均按MHD中是否发生IDH进行分组,并接受了“MHD中发生IDH常见易患因素调查表”评估,比较各种观察指标。结果 191例接受MHD治疗的终末期肾病患者中,维持性血液透析中发生IDH患者57例(29.84%),IDH组中透析总时间、透析频率、血红蛋白(Hb)及透析充分性标准值(Kt/V)均明显低于对照组,而IDH组中平均年龄、超滤率、血尿素氮(BUN)、血清磷(P)、血甲状旁腺素(PTH)及透析期间体质量增加量(IDWG)均明显高于对照组(P<0.01或P<0.05)。结论大龄、透析时间短、频度少及质量差、电解质紊乱和营养现况不佳均可能是终末期肾病患者MHD中发生IDH的易患因素。
Objective To analyze the common risk factors for developing associated hypertension (IDH) in maintenance hemodialysis (MHD) in patients with end-stage renal disease. Methods Ninety-one patients with end-stage renal disease treated by MHD in the Department of Nephrology and Blood Purification Center of Nephrology were grouped according to whether there was IDH in the MHD and received a “Survey of Common Risk Factors for IDH in MHD” to compare various observations index. Results Among the 191 patients with end-stage renal disease undergoing MHD, 57 patients (29.84%) had IDH during maintenance hemodialysis, and the total dialysis time, dialysis frequency, hemoglobin (Hb) and dialysis adequacy standard (Kt / V) were significantly lower than those in the control group, but the average age, ultrafiltration rate, blood urea nitrogen (BUN), serum phosphorus (P), parathyroid hormone (PTH) IDWG) were significantly higher than the control group (P <0.01 or P <0.05). Conclusions Older age, short dialysis time, less frequent and poor quality, electrolyte imbalance and poor nutritional status may be risk factors for IDH in patients with end-stage renal disease.