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目的:分析CT引导下组织间插植放射治疗软组织肉瘤的临床效果。方法:选取2003年11月至2010年5月来我院治疗的软组织肉瘤患者22例,采用CT引导下组织间插植放射进行治疗,主要利用的是直线加速器6-MVX线,外照射20-30Gy,后同步开始高剂量率铱-192后装对患者进行治疗,每次剂量在9Gy左右,总剂量要求在24至30Gy之间,患者在进行组织间插植治疗的同时不能开展外照射,外照射的总剂量要求在50至60Gy之间。结果:经过组织间插植放射治疗后,软组织肉瘤患者压迫症状缓解率为82%,其中3例发生远处转移,2例带瘤生存出现副反应,总体治疗效果明显。结论:利用CT引导下组织间插植放射治疗软组织肉瘤患者具有明显治疗效果,值得推广使用在软组织肉瘤患者的临床治疗中。
Objective: To analyze the clinical effect of CT-guided interstitial implantation of soft tissue sarcomas. Methods: Twenty-two patients with soft tissue sarcoma treated in our hospital from November 2003 to May 2010 were enrolled in this study. CT-guided interstitial irradiation was used to treat the patients. The main applications were 6-MVX linear accelerator and 20- 30Gy, post-synchronization began high dose rate of iridium -192 after the installation of the patient for treatment, each dose of about 9Gy, the total dose required between 24 to 30Gy, interstitial implantation of patients in the same time can not carry out external irradiation, The total dose of external radiation requirements in the 50 to 60Gy between. Results: The rate of oppression of soft tissue sarcoma was 82% after radiotherapy. The distant metastasis occurred in 3 cases and the side effects occurred in 2 cases. The overall curative effect was obvious. Conclusion: CT-guided interstitial implantation of radiotherapy soft tissue sarcoma patients with significant therapeutic effect, it is worth promoting the use of soft tissue sarcoma in patients with clinical treatment.