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目的动态监测新诊断2型糖尿病(T2DM)患者血糖漂移的细节及波动趋势。方法采用动态血糖监测系统(CGMS)对40例T2DM患者进行连续72h的血糖监测。结果CGMS所测的血糖值与血浆血糖值及指端血糖值均呈显著正相关(r=0.92,r=0.93,P均<0.001)。患者1d中血糖较高的时间段为早、中、晚餐后2h,尤其是早餐后2h最高。上午6时～11时是血糖高峰最集中(62.5%)的时间段,而60.5%的血糖低谷值出现在上午1时～6时,尤其是上午3时最低。血糖>7.8及11.1mmol/L所占的时间百分比分别为92(38～100)%和60(18～100)%;结论动态血糖监测能较详细地显示T2DM患者血糖水平波动的特征,对强化治疗的糖尿病患者的胰岛素精细调节提供了临床依据。
Objective To dynamically monitor the details of blood glucose drift and trend of fluctuation in newly diagnosed type 2 diabetes mellitus (T2DM) patients. Methods Forty patients with T2DM underwent continuous 72h blood glucose monitoring by dynamic glucose monitoring system (CGMS). Results The blood glucose levels measured by CGMS were positively correlated with plasma glucose and finger blood glucose (r = 0.92, r = 0.93, P <0.001). Patients with high blood sugar in the 1d period of time as early, middle and 2h after dinner, especially after 2h after breakfast the highest. 6: 00 am to 11: 00h is the time period with the highest concentration of blood glucose (62.5%), while 60.5% of the patients with low blood glucose level appear at 1: 00 am to 6:00 am, especially at 3:00 am. Blood glucose> 7.8 and 11.1 mmol / L accounted for 92 (38-100)% and 60 (18-100)%, respectively; Conclusion The dynamic blood glucose monitoring can show the characteristics of blood glucose level fluctuation in T2DM patients in more detail, The treatment of diabetic patients with fine-tuning of insulin provides a clinical basis.