引言大多数生物化学反应具有立体特异性,三羧酸循环的各个步骤的化学反应虽早已阐明,但是其间的许多由酶催化的立体特异反应的机制,是随着人们认识的深化而逐步弄清楚的。下面的一些剖析,对每一过程作了合理的说明,使我们更好地体会到我们自己身体里经常发生的变化是如何微妙地安排的! 第一步柠檬酸的形成该步是由柠檬酸合成酶催化的,反应如图1所示。 INTRODUCTION Most biochemical reactions are stereospecific and the chemical reaction at each step of the tricarboxylic acid cycle has long been elucidated, but many of the mechanism of enzyme-catalyzed stereospecific reactions are gradually clarified as people’s understanding deepens of. Some of the following analysis, a reasonable explanation of each process, so that we better understand how often our own body changes are subtle arrangement! The first step in the formation of citric acid This step is made of citric acid Synthase-catalyzed, the reaction shown in Figure 1.