过氧化物酶体增殖物激活受体 (PPARs)属 型核受体超家族成员 ,是一类由配体激活的核转录因子。这类受体在体内分布广泛 ,参与脂肪细胞分化 ,调控脂类和糖的代谢 ,参与单核 /巨噬细胞激活及肿瘤细胞分化等多种过程。 PPARs处于多种信号转导途径的交叉点 ,与代谢综合征关系密切 A member of the nuclear receptor superfamily of peroxisome proliferator-activated receptor (PPARs) genotypes, is a family of ligand-activated nuclear transcription factors. These receptors are widely distributed in the body, participate in adipocyte differentiation, regulate the metabolism of lipids and carbohydrates, participate in a variety of processes such as monocyte / macrophage activation and tumor cell differentiation. PPARs are at the crossroads of multiple signal transduction pathways and are closely related to the metabolic syndrome