论文部分内容阅读
目的:研究和探讨抗甲状腺过氧化酶抗体与早期反复自然流产的相关性分析。方法:选取我院收治的80例反复自然流产患者(病例组)为研究对象,按照流产的不同时间段分为A组(40例,早期流产)和B组(40例,晚期流产),另取40例健康育龄妇女作为对照组,对比检测结果。结果:病例组反复自然流产患者TPO-Ab、TG-Ab水平及阳性率显著高于对照组,差异有统计学意义(P<0.05);A组早期流产患者TPO-Ab、TG-Ab水平及阳性率显著高于B组晚期流产患者,差异有统计学意义(P<0.05);进行Logistic回归分析,结果显示仅TPO-Ab阳性结果具有统计学意义(P<0.05)。结论:抗甲状腺过氧化酶抗体与早期反复自然流产有密切关系,在临床作业中,仔细观察孕妇妊娠期血清抗甲状腺过氧化酶抗体水平,以便早期发现孕妇不良妊娠结局。
Objective: To study and explore the correlation between anti-thyroid peroxidase antibody and early recurrent spontaneous abortion. Methods: A total of 80 patients with recurrent spontaneous abortion (case group) admitted to our hospital were enrolled in this study. They were divided into group A (40 cases) and group B (40 cases), according to different periods of abortion. Take 40 healthy women of childbearing age as a control group, comparing the test results. Results: The levels of TPO-Ab, TG-Ab and the positive rate of patients with recurrent spontaneous abortion in the case group were significantly higher than those in the control group (P <0.05), and the levels of TPO-Ab, TG-Ab The positive rate of TPO-Ab was significantly higher than that of patients with advanced abortion in group B (P <0.05). Logistic regression analysis showed that the positive results of TPO-Ab alone were statistically significant (P <0.05). Conclusion: Anti-thyroid peroxidase antibody is closely related to early recurrent spontaneous abortion. In clinical practice, the level of serum anti-thyroid peroxidase antibody in pregnant women was carefully observed to find out the adverse pregnancy outcomes in pregnant women at early stage.