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[目的]观察化浊和胃散结汤联合FOLFOX方案治疗晚期胃癌的疗效。[方法]将66例患者随机分为2组,治疗组36例,采用中药化浊和胃散结汤联合FOLFOX方案治疗,对照组30例,单纯采用FOLFOX方案化疗。[结果]治疗组和对照组有效率分别为72.22%和46.67%,差异有统计学意义(P<0.05);治疗组半年生存率和1年生存率分别为75.00%和47.22%,对照组半年生存率和1年生存率分别为46.67%和23.33%。2组半年生存率及1年生存率比较,差异均有统计学意义(P<0.05)。[结论]化浊和胃散结汤联合FOLFOX方案治疗晚期胃癌能延长患者生存期。
[Objective] To observe the curative effect of Huazhuo Weisujie Decoction combined with FOLFOX regimen in the treatment of advanced gastric cancer. [Methods] 66 patients were randomly divided into two groups, the treatment group of 36 cases, using the traditional Chinese medicine Huazhuo Wei San Sanjie Decoction combined with FOLFOX regimen, the control group of 30 cases, simple treatment with FOLFOX regimen. [Results] The effective rates of the treatment group and the control group were 72.22% and 46.67%, respectively, with significant difference (P <0.05). The half-year and 1-year survival rates of the treatment group and the control group were 75.00% and 47.22% The survival rate and 1-year survival rate were 46.67% and 23.33% respectively. The 2-year survival rates and 1-year survival rates of two groups were significantly different (P <0.05). [Conclusion] Huazhuo Weiseljie Decoction combined with FOLFOX regimen can prolong the survival of patients with advanced gastric cancer.